BACKGROUND: SALVIA IS AN IMPORTANT GENUS OF THE LAMIACEAE FAMILY CONSISTING OF OVER 900 SPECIES. DITERPENOIDS, TRITERPENOIDS AND POLYPHENOLS ARE VERY COMMON IN PLANTS OF THIS GENUS. MOST SALVIA SPECIES HAVE BEEN EXTENSIVELY INVESTIGATED FOR THEIR POTENTIAL BIOLOGICAL PROPERTIES. [1] S. LERIIFOLIA SHOWS STRONG ANTIBACTERIAL AND ANTIFUNGAL ACTIVITIES. [2] METHODS: THE AERIAL PARTS OF SALVIA LERIIFOLIA WERE COLLECTED FROM TROPICAL REGIONS OF THE KHORASSAN. AERIAL PARTS (4.5KG) WERE EXTRACTED FIVE TIMES WITH HEXAN. THE SOLVENT WAS EVAPORATED UNDER VACUMM TO GIVE 120 G OF EXTRACT. THE EXTRACT WAS CHROMATOGRAPHED ON SILICA GEL COLUMN (230-400 MESH) AND ELUTED WITH VARYING PORTIONS OF N-HEXANE, ETOAC AND METHANOL. AT THE END OF THIS A PURE POWDER WERE PURIFIED. ITS STRUCTURE HAS BEEN ESTABLISHED BY (1HNMR, 13CNMR AND HMQC), AS WELL AS HRESIMS.RESULTS: FRACTIONATION OF HEXANE EXTRACT OF S. LERIIFOLIA LED TO THE ISOLATION OF A TRITERPENOID (1).

THE GENUS SALVIA BELONGS TO THE LAMIACEAE AND ENCOMPASSES 900 SPECIES WORLDWIDE OF WHICH CA.17 INDIGENOUS SPECIES ARE FOUND IN IRAN [1, 2]. IN THIS PAPER PHYTOCHEMICAL INVESTIGATION OF SALVIA URMIENSIS AS AN ENDEMIC PLANT OF IRAN WAS CARRIED OUT. SIX COMPOUNDS WERE ISOLATED FROM ITS HEXANE EXTRACT AND THEIR STRUCTURES WERE ELUCIDATED BY 1D (1H AND 13C), 2D-NMR AND ALSO X-RAY CRYSTALLOGRAPHY...

THE GENUS SALVIA BELONGS TO THE LAMIACEAE FAMILY AND COMPRISES NUMEROUS SPECIES THAT HAVE BEEN USED SINCE ANCIENT TIMES FOR THE TREATMENT OF SEVERAL DISORDERS. DITERPENOIDS, TRITERPENOIDS AND POLYPHENOLS ARE VERY COMMON IN PLANTS OF THIS GENUS. MOST SALVIA SPECIES HAVE BEEN EXTENSIVELY INVESTIGATED FOR THEIR POTENTIAL BIOLOGICAL PROPERTIES [1].S. LERIIFOLIA BENTH, THAT WAS INTRODUCED IN THE IRANIAN FLORA IN 1982, GEOGRAPHICALLY GROWS IN THE SOUTHERN AND TROPICAL REGIONS OF THE KHORASSAN AND SEMNAN PROVINCES, IRAN. DIFFERENT PHARMACOLOGICAL ACTIVITIES OF THIS PLANT, SUCH AS THE ATTENUATION OF MORPHINE DEPENDENCE, HYPOGLYCEMIC, ANALGESIC, AND ANTI-INFLAMMATORY ACTIVITIES, AND ANTICONVULSANT, ANTIULCER, AND ANTIBACTERIAL EFFECTS, WERE EVALUATED [2].HEREIN, WE REPORT THE ISOLATION AND STRUCTURAL ELUCIDATION OF TERPENOID CONSTITUENT OF S. LERIIFOLIA. FRACTIONATION OF A HEXANE EXTRACT OF THE AERIAL PARTS OF THIS PLANT LED TO THE ISOLATION OF LABDANE DITERPENOID. ITS STRUCTURE HAVE BEEN ESTABLISHED BY HIGH-FIELD NMR TECHNIQUES (1HNMR, 13CNMR, 1H-1H COSY AND HMQC).

LAMIACEAE, ALSO CALLED LABIATAE, WITH 236 GENERA AND MORE THAN 7,000 SPECIES I THE LARGEST FAMILY OF THE ORDER LAMIALES. IT IS IMPORTANT TO HUMANS FOR FLAVOUR, FRAGRANCE, OR MEDICINAL AND MANY OTHER PROPERTIES. …

BACKGROUND AND AIM: HELICOBACTER PYLORI IS A GRAM-NEGATIVE, ROD-SPIRAL SHAPE BACTERIUM AND ONE OF THE MOST IMPORTANT AGENTS IN CHRONIC GASTRITIS, PEPTIC ULCERS AND GASTRIC ADENOCARCINOMA IN HUMAN. VITEX TRIFOLIA L. HAS BEEN TRADITIONALLY USED IN THE TREATMENT OF GASTROINTESTINAL DISORDERS.HOWEVER, ITS ACTUAL PROPERTIES HAS NOT BEEN SCIENTIFICALLY PROVEN….

GRAMMOSCIADIUM PLATYCARPUM IS ONE OF THE THREE ENDEMIC SPECIES OF GRAMMOSCIADIUM GENUS (APIACEAE ) IN IRAN, THAT GROWS IN THE WESTERN AREAS OF IRAN. THIS GENUS IS REPRESENTED IN THE IRANIAN FLORA BY 8 SPECIES.

HERACLEUM PERSICUM L. IS ONE OF THE MOST IMPORTANT SPECIES FROM HERACLEUM GENUS BELONGING TO THE FAMILY OF UMBELLIFERAE. THIS AROMATIC PLANT USED AS A FLAVORING INGREDIENT IN MANY IRANIAN FOOD PRODUCTS.

THE GENUS ARTEMISIA (ASTERACEAE) IS THE LARGEST AND MOST WIDELY DISTRIBUTED ONE OF THE APPROXIMATELY 60 GENERA BELONGING TO THE TRIBE ANTHEMIDEAE. THIS GENUS COMPRISES A VARIABLE NUMBER OF SPECIES.

SCROPHULARIA IS A GENUS OF THE FAMILY SCROPHULARIACEAE. THIS GENUS INCLUDES ABOUT 3000 SPECIES AND 220 GENERA WHICH ARE WIDELY DISTRIBUTED IN THE ALL REGIONS OF THE WORLD, ESPECIALLY IN THE MEDITERRANEAN AREA [1]. DCM AND N-HEXANE EXTRACT OF THIS PLANT WERE ANALYZED BY GC-MS. …